Careers

Amunix offers an exciting and fast-paced scientific environment. We are seeking highly motivated and independent individuals to join our discovery and development efforts.

Current Career Opportunities at Amunix:

(Fermentation) Process Development Manager

Job Purpose

Manage the upstream process development activities and support CMC strategies across the product development cycle, including strain development, fermentation process development, process scale up, tech transfer and analytical implementation.  Ensure that products manufactured to support pre-clinical and clinical studies are in compliance with the requisite regulations and guidelines.

Position Duties and Responsibilities

  • Leads and direct fermentation process development team efforts in the development and optimization of strain/fermentation development processes.
  • Deep understanding of strain/expression optimization and fermentation concepts, practices, and procedures (including process scale-up and tech transfer).
  • Ability to identify and implement the necessary analytical tools to ensure the success process development efforts from research through to clinical and/or /commercialization.
  • Responsible for thorough record keeping by staff, such that accurate records, timely databasing and ease-of-access to results is maintained.
  • Prepare protocols for- and reports of- completed projects for presentation to company personnel, external partnering organization and/or publication.
  • Provide oversight and support technical transfer of upstream processes to partnering entities.  Foster and maintain strong relationships with contract manufacturers, testing labs and other partnering entities including construct development and cell banking entities.
  • Relies on experience and judgment to plan and accomplish tasks efficiently.
  • Support successful preparation of CMC sections for regulatory submissions.
  • Be able to prepare peer-reviewed publications.
  • Receive and implement strategic directives from Senior Management.

Key Requirements/Degree Requirements

  • BS/MS from a qualified university in Life Science/Chemistry/Engineering or related fields and 5-10 years of related work experience including supervisory roles, or
  • PhD degree from a qualified university in Life Science/Chemistry/Engineering or related fields and 3-5 years of related work experience including supervisory roles

Special Skills and Qualifications

  • Ability to communicate effectively, both verbally and written.
  • Must be highly organized, analytical, accurate and detail oriented.
  • Must have hands-on familiarity with standard strain development/optimization techniques as well as bench-scale fermentation equipment and associated analytical equipment.     
  • Must be able to read and interpret technical, trade documents, and journals.
  • Must be able to analyze and prioritize assignments; also must judge the amount of time spent for an expected outcome, and manage resources according to the importance of a project and the type of information needed.
  • Must be able to lead a team, manage personnel and multiple projects.
Research Associate II/III, Analytical Chemistry

Amunix Operating, Inc. is a biotech company in Mountain View, CA focused on the design and preclinical development of protein pharmaceuticals with an extended serum half-life through the application of our XTEN technology platform. XTEN is a hydrophilic, unstructured polypeptide that imparts a number of favorable properties on the molecules to which it is attached. By fusing existing, clinically proven products to XTEN, we generate improved versions or "bio-superiors." Beyond the advantage of less frequent dosing, XTENylation also stabilizes drug concentration, therefore preventing the side effects, such as toxicity and reduced efficacy, associated with deviation from the therapeutic window. More information can be found at www.amunix.com

Job Description

Amunix is currently seeking a highly-motivated candidate to fill a Research Associate II/III position in its Analytical Chemistry group.

Qualifications

  • RA II: Bachelor’s degree from a qualified university in Life Science/Chemistry or related fields, or equivalent, and 2-3 years of relevant work experience.
  • RA III: Master’s degree from a qualified university in Life Science/Chemistry or related fields and 2 years of relevant work experience, or Bachelor’s degree and 3-5 years of relevant work experience.
  • Good understanding of protein biochemistry and chromatography/analytical concepts is required.
  • Experience with protein analytical techniques such as SDS‑PAGE, Western blotting, SEC-HPLC, IEX-HPLC, MALDI-TOF-MS is required.
  • Demonstrated ability to draft experimental plans, execute and document experiments, analyze data, and write technical reports with minimal supervision is preferred.
  • Experience with current good manufacturing practices (cGMP) is a plus.
  • Proficiency with MS PowerPoint, Excel and Word.

General Skills

  • Ability to communicate effectively, both verbally and written.
  • Must be highly organized, analytical, accurate and detail oriented.
  • Must have knowledge of standard reference/information sources and library skills; must be able to read and interpret technical, trade documents, and journals.
  • Must be able to work independently, as well as part of an interdisciplinary team and work with minimal supervision.

Responsibilities

  • Performs analytical testing of samples as required by protocol or specified data gathering requirements. 
  • Conducts hands-on research in analytical method development.
  • Maintains and updates calibration of analytical equipment and facility.
  • Thorough record keeping in database(s) and notebook entries.
  • Collates data and prepares summaries of completed activities for presentation to management level staff, incorporation into reports or archival files/databases.   

We offer

  • Incorporating highly collaborative and motivated working environment, in a company in full expansion.
  • Comprehensive Benefit package available, including Health, Dental, Vision, Short term and long term Disability.
  • Job title and compensation will be based on candidate experience.

Job Requirements

  • The position requires on-site participation in planning, organization (i.e., materials preparation, equipment set-up), execution (i.e., monitoring processes, procedures, performing analytical tests, documentation) and follow-up of experiments. This may require assembling, manipulating and operating equipment and apparatuses for several hours at a time.
  • The position requires the ability to lift up to 40 lbs.
  • The position requires the ability to walk and/or stand for extended (hours) periods at a time.
Research Associate I/II Fermentation

Job Purpose

  • Perform research and essential laboratory studies in strain- and fermentation development under the instructions of the area supervisor/manager and to provide support to staff assisting with the research.

Research Associate I…

Position Duties and Responsibilities

  • Conducts hands-on research in strain- and fermentation development.
  • Supervisor/Manager to provide prioritization on research protocols, experiments and testing.
  • Maintains and updates calibration of fermentation equipment, ancillary analytical equipment and facility.
  • Performs analytical testing of samples as required by protocol or specified data gathering requirements. 
  • Thorough record keeping in database(s) and notebook entries.
  • Collates data and prepares summaries of completed activities for presentation to management level staff, incorporation into reports or archival files/databases. 

Key Requirements/Degree Requirements

  • Bachelor’s degree from a qualified university in Life Science/Chemistry or related fields, or equivalent, or
  • Associate’s degree in a scientific related field, with 2+ years related work experience, or
  • 5+ years equivalent work experience in scientific related field

Special Skills and Qualifications

  • Ability to communicate effectively, both verbally and written
  • Must be highly organized, analytical, accurate and detail oriented
  • Must have some basic knowledge of standard reference/information sources and library skills; must be able to read and interpret technical, trade documents, and journals
  • Must have basic knowledge of strain manipulation, screening and optimization.
  • Must have basic training in microbial techniques and associated analytical tools and familiarity with fermentation operations and principles. 
  • Must be able to work independently, as well as part of an interdisciplinary team
  • Training will be provided in required disciplines

Research Associate II…

Position Duties and Responsibilities

  • Conducts hands-on research in strain- and fermentation development.
  • Spends some time developing plans for the project. Supervisor/Manager to provide prioritization on research protocols, experiments and testing.
  • Maintains and updates calibration of fermentation equipment, ancillary analytical equipment and facility.
  • Performs analytical testing of samples as required by protocol or specified data gathering requirements. 
  • Thorough record keeping in database(s) and notebook entries.
  • Collates data and prepares summaries of completed activities for presentation to management level staff, incorporation into reports or archival files/databases. 

Key Requirements/Degree Requirements

  • Bachelor’s degree from a qualified university in Life Science/Chemistry or related fields, or equivalent, and 1-2 years of relevant work experience or
  • Associate’s degree in a scientific related field, with 3-4 years relevant work experience, or
  • 6+ years equivalent work experience in scientific related field

Special Skills and Qualifications

  • Ability to communicate effectively, both verbally and written
  • Must be highly organized, analytical, accurate and detail oriented
  • Must have basic knowledge of strain manipulation, screening and optimization. Must have academic or industry experience with microbial techniques and associated analytical tools as well as fermentation operations and principles. 
  • Must be able to analyze and prioritize assignments; also must judge the amount of time to spend for the expected outcome, according to the importance of a project and the type of information needed
  • Must be able to work independently, as well as part of an interdisciplinary team

We offer

  • Incorporating highly collaborative and motivated working environment, in a company in full expansion.
  • Comprehensive Benefit package available, including Health, Dental, Vision, Short term and long term Disability.
  • Job title and compensation will be based on candidate experience.

Job Requirements

  • The position requires on-site participation in planning, organization (i.e., materials preparation, equipment set-up), execution (i.e., monitoring processes, procedures, performing analytical tests, documentation) and follow-up of experiments. This may require assembling, manipulating and operating equipment and apparatuses for several hours at a time.
  • The position requires the ability to lift up to 40 lbs.
  • The position requires the ability to walk and/or stand for extended (hours) periods at a time.

In your application, please include a brief cover letter detailing your fit for the position as well as a CV or resume.

Scientist – Protein Conjugation Chemistry

Amunix Operating, Inc. is a biotech company in Mountain View, CA focused on the design and preclinical development of protein pharmaceuticals with an extended serum half-life through the application of our XTEN technology platform. XTEN is a hydrophilic, unstructured polypeptide that imparts a number of favorable properties on the molecules to which it is attached. By fusing existing, clinically proven products to XTEN, we generate improved versions or "bio-superiors." Beyond the advantage of less frequent dosing, XTENylation also stabilizes drug concentration, therefore preventing the side effects, such as toxicity and reduced efficacy, associated with deviation from the therapeutic window. More information can be found at www.amunix.com

Job Description

Amunix is currently seeking a highly-motivated candidate to fill Scientist – Protein Conjugation Chemistry position. Responsibilities will include:

  • Developing methods for conjugation of small molecules, peptides and proteins to XTEN protein polymers
  • Developing new multivalent and multispecific formats for XTEN conjugates
  • Planning and executing production of XTEN-drug conjugates for in vivo studies
  • Developing and performing analytical assays to ensure conjugate quality

Qualifications

  • Ph.D. in Chemistry, Biochemistry, Chemical Engineering, or a related field
  • Hands-on experience in organic synthesis and protein chemistry
  • Working knowledge of protein purification (conventional chromatography, FPLC, preparative HPLC) and protein analytics (SEC-, IEX-, RP-HPLC, mass spectrometry, light scattering, etc.)
  • Must be able to work independently in a fast-paced, project-driven environment
  • Must be able to communicate effectively, both verbally and written
  • Must be highly organized, analytical, accurate and detail oriented
  • Must have knowledge of standard reference/information sources and library skills; must be able to read and interpret technical, trade documents, and journals
  • Must be able to analyze and prioritize assignments; also must judge the amount of time to spend for the expected outcome, according to the importance of a project and the type of information needed
  • Must be able to lead a team, manage personnel and projects

Physical Requirements

  • The position requires the ability to lift up to 40 lbs.
  • The position requires the ability to walk and/or stand for extended (hours) periods at a time.

We offer

  • Highly collaborative and motivated working environment in a company experiencing high growth and undergoing a significant expansion
  • Comprehensive benefit package available, including health, dental, vision, short term and long term disability.
  • Job title and compensation will be based on candidate experience.

Please send applications to HR@amunix.com and mention job code P14_11 in the subject line of your application.  Please do not contact Amunix about your application. Previous applicants to Amunix need not apply.

Senior Scientist/Scientist Protein Chemistry/Protein Engineering

Amunix is a rapidly growing biotechnology startup located in Mountain View, CA (San Francisco Bay; Silicon Valley).  Amunix is focused on applying its proprietary XTEN protein polymer technology platform to a wide range of therapeutic areas. Our efforts are centered around partnerships with pharma and biotech companies, which greatly increases the reach of our technology.

Responsibilities will include:

  • Plan and manage the engineering of XTEN fusion proteins
  • Manage partner interactions
  • Protein expression using microbial systems (E. coli)
  • Protein purification
  • Bioconjugation
  • Protein characterization developing and performing robust biochemical assays to ensure protein quality and integrity

Requirements:

  • Ph.D. in Biochemistry, Chemical Engineering, or a related field
  • Strong background in protein engineering (for example: library design, screening, antibody fragments, phage display)
  • Working knowledge of protein characterization: FPLC/HPLC, peptide mapping, light scattering, ELISA, etc)
  • Extensive experience with the development and validation of analytical protein assays
  • Ability to work independently in a fast-paced, project-driven environment
  • Excellent presentation and project management skills are essential for this position
  • Ability to supervise and mentor other employees

Company Description
We are a biopharmaceutical company developing first-in-class products using our novel half-life extension technology. 

  • Contribute to a company experiencing high growth and  undergoing significant expansion
  • Work in a highly collaborative and motivated working environment
  • Comprehensive Benefit package available, including Health, Dental, Vision, Short term and long term Disability
  • Compensation will be based on candidate experience

Please send applications to HR@amunix.com and mention job code P14_06 in the subject line of your application.