Frazier Healthcare Partners
Patrick is a Managing General Partner of Frazier’s Life Sciences team. He joined the firm in 1999 and opened Frazier’s Menlo Park office in 2003. Throughout his 13 years as a General Partner, Patrick has led or co-led investments across nearly 20 companies, including ARMO (acquired by Eli Lilly), Ignyta (acquired by Roche), Tobira Therapeutics (acquired by Allergan), Marcadia (acquired by Roche), Calixa (acquired by Cubist), Cerexa (acquired by Forest), PreCision Dermatology (acquired by Valeant), MedPointe (acquired by Meda), and Collegium (NASDAQ: COLL). He currently serves on the boards of Flashlight Therapeutics, Imago BioSciences, Iterum Therapeutics (NASDAQ: ITRM), Mirum Pharmaceuticals, ScoutBio, Silvergate Pharmaceuticals and SutroVax.
Prior to joining Frazier, Patrick helped develop McKinsey & Company's West Coast biotechnology consulting practice, where he led projects involving mergers and acquisitions, product launches, sales force optimization, corporate partnering, and research prioritization.
Patrick received his M.B.A. from Harvard Business School. He also holds a B.A. from the University of North Carolina at Chapel Hill, where he is a Phi Beta Kappa graduate and Morehead Scholar.
Rich Heyman, Ph.D.
Chairman of the Board of Directors
Dr. Rich Heyman is an accomplished scientist and biopharma executive with over 25 years of experience leading innovative biotechnology companies. Dr. Heyman previously served as Chief Executive Officer of Seragon Pharmaceuticals, a company focused on drugs targeting hormone dependent cancers, until its acquisition by Roche in 2014. Dr. Heyman was also the co-founder and Chief Executive Officer of Aragon Pharmaceuticals, which was acquired by Johnson & Johnson in 2013. Prior to Aragon, Dr. Heyman held leading scientific and business roles at several biotechnology companies, including X-Ceptor Therapeutics and Ligand Pharmaceuticals. At Ligand, Dr. Heyman led the development of Panretin® and Targretin®, which were approved by the FDA for the treatment of cancer.
In addition to serving on the Amunix Pharmaceuticals Board of Directors, Dr. Heyman is a Director at Gritstone Oncology, Yumanity Therapeutics, Metacrine Inc., Vividion Therapeutics, Mavupharma, and ORIC Pharmaceuticals. He is also the Vice Chairman of The Salk Institute and author or inventor of more than 120 publications and patents.
Dr. Heyman was an NIH postdoctoral fellow at the Salk Institute and received a Ph.D. in pharmacology from the University of Minnesota and a B.S. in chemistry from the University of Connecticut.
Volker Schellenberger, Ph.D.
President and Chief Technology Officer
Dr. Volker Schellenberger is a co-founder of Amunix and currently serves as President and Chief Technology Officer. Dr. Schellenberger has extensive industry experience in protein engineering and drug discovery. Previously, he headed the Protein Engineering department at Genencor, where he invented combinatorial consensus mutagenesis, selection by micro-compartmentalization, as well as mutator technology. In addition, he initiated and led collaborations with Seattle Genetics that focused on antibody-enzyme fusion proteins. Prior to his work on biotherapeutics, Dr. Schellenberger directed projects optimizing enzymes for industrial applications as well as microbes for metabolic pathway engineering.
Dr. Schellenberger received his Ph.D. from Leipzig University, where he studied protease catalyzed peptide synthesis. After postdoctoral studies at the Institute for Protein Research in Pushchino (Russia), he moved to the University of Göttingen where he developed a novel method for the production of peptides from recombinant peptide-multimers. After a postdoctoral fellowship with Bill Rutter at the University of California, San Francisco, Dr. Schellenberger joined Genencor in 1994. Dr. Schellenberger is the author of over 40 scientific papers and an inventor on more than 70 issued and pending patent applications. He is also the recipient of the Karl Lohman award of the German Society of Biochemists.
James N. Topper, M.D., Ph.D.
Frazier Healthcare Partners
Jamie is a Managing General Partner of Frazier Healthcare Partners' Life Sciences team. Since joining Frazier in 2003, he has led and served as a board member for a number of Frazier’s successful life sciences investments, including Acerta Pharma BV (sold to AstraZeneca), Calistoga Pharmaceuticals (co-founder, sold to Gilead Sciences), Rempex (sold to The Medicines Company), Incline (co-founder, sold to The Medicines Company), Alnara (sold to Lilly), Portola (co-founder, NASDAQ: PTLA), CoTherix (sold to Actelion), and Threshold (NASDAQ: THLD). He currently represents Frazier on the boards of Alcresta Therapeutics, Allena Pharmaceuticals (NASDAQ: ALNA), Alpine Immune Sciences (NASDAQ: ALPN), AnaptysBio (NASDAQ: ANAB), Aptinyx (NASDAQ: APTX), Entasis Therapeutics (NASDAQ: ETTX), and Mavupharma. He is also a board observer for Sojournix.
Prior to joining Frazier, Jamie was the head of cardiovascular R&D at Millennium Pharmaceuticals and ran Millennium San Francisco (formerly COR Therapeutics). Before the merger of COR and Millennium, he served as the Vice President of Biology at COR and was responsible for all research activities. He served on the medical school faculties at Stanford and Harvard Medical School prior to joining COR.
Jamie received his M.D. and Ph.D. in Biophysics from Stanford and holds a B.S. from the University of Michigan. He did his postgraduate training in Internal Medicine and Cardiovascular Disease at the Brigham and Women's Hospital in Boston. He has authored over 50 publications and was the recipient of a Howard Hughes Scholars Award while on the faculty at Stanford.
Angie You, Ph.D.
Chief Executive Officer
Angie serves as Chief Executive Officer of Amunix Pharmaceuticals Inc. Prior to joining Amunix, Dr. You served as Chief Business & Strategy Officer and Head of Commercial at Sierra Oncology (NASDAQ: SRRA), a publicly listed hematology and oncology drug development company, where she helped the company through a successful initial public offering. She also led the company’s strategic and transactional business and commercial efforts, including building its robust pipeline through acquisition and licensing of several product assets. Prior to Sierra, Dr. You served as Chief Business Officer of Aragon Pharmaceuticals, a private oncology drug discovery and development company, where she was responsible for finance, operations, human resources, and business development. At Aragon, Dr. You helped secure several rounds of financing as well as leading the business development process that resulted in the company’s acquisition by Johnson & Johnson. In previous roles, Dr. You served as Chief Business Officer at Synosia Therapeutics and Ren Pharmaceuticals. Before joining Ren Pharmaceuticals, Dr. You focused on new company formation at Venrock Ventures.
Dr. You earned a Ph.D. in Biochemistry from Harvard University and a B.A. in Chemistry from Harvard College.