Senior Scientist, Protein Engineering and Protein Chemistry

Job Description

Amunix Pharmaceuticals Inc. is seeking a highly-driven and innovative individual to join our Research and Discovery group. The candidate will be responsible for the design and optimization of multi-specific protein therapeutics with focus on oncology targets. He/She must be highly motivated and collaborative to thrive in a fast-paced, dynamic work environment.

Positions Duties and Responsibilities

  • Design and optimize molecules through a combination of rational design and empirical screening
  • Engineer proteins (with a focus on antibody fragments) to improve folding, stability, optimized binding, and/or increased production yield
  • Perform small-scale/medium throughput protein expression (E. coli) and purification
  • Work closely with other team members to evaluate and characterize target molecules in a variety of in vitro and in vivo models
  • Function as a project leader to coordinate efforts, define timelines and deliverables


  • Ph.D. in Biological Sciences (Biochemistry, Protein Chemistry, Enzymology) or a related field with at least 2 years of post-graduate experience in either an academic or industrial setting
  • Strong scientific background in protein engineering and protein chemistry
  • Hands-on experience with medium throughput protein expression and characterization (Octet or similar)
  • Experience with multiplex assays (binding and/or kinetics) is preferred
  • Ability to think creatively to identify and solve scientific problems
  • Extensive knowledge of the scientific literature
  • The ability to manage multiple projects in parallel, communicate clearly and effectively and build open and collaborative relationships is essential
  • Ability to effectively work independently and participate in multi-disciplinary teams
  • Strong interpersonal aptitude and excellent oral and written communication skills
  • Physical ability to lift up to 40 lbs and work at the lab bench for extended periods of time

About Amunix

We are a biopharmaceutical company developing highly innovative biotherapeutics with best-in-class therapeutic index. Amunix products are based on our ProTIA (Protease Triggered Immune Activator) and XTEN protein polymer platforms. In addition to our internal pipeline we maintain active collaborations with many top tier pharmaceutical and biotechnology companies (Roche, Celgene, Genentech, Bioverativ/Sanofi). As employee you will be able to:

  • Participate in the discovery of potentially life-saving pharmaceuticals
  • Work in a highly collaborative and motivating working environment
  • Receive a comprehensive benefits package, including Health, Dental, Vision, Life Insurance, Short-term/Long Term Disability, matching 401(k) plans, and free daily lunches
  • Receive competitive compensation based on candidate experience

Amunix is located in Mt. View, California. Amunix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics.  In addition to federal law requirements, Amunix complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities.  This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation and training.